BRG1 Mouse Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Number: RA10867-50, RA10867-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store At/In: -20°C/1 year
Recommended Dilutions: WB Dilution 1:1000 icc Dilution 1:50
Alternative Names: ATP dependent helicase SMARCA4;ATP-dependent helicase SMARCA4;BAF 190;BAF190;BAF190A;Brahma protein homolog 1;Brahma protein like 1;BRG1;BRG1 associated factor 190A;BRG1 protein;BRG1-associated factor 190A;BRM/SWI2 related gene 1;Global transcription activator homologous sequence;global transcription activator snf2l4;Homeotic gene regulator;hSNF2b;Mitotic growth and transcription activator;MRD16;Nuclear protein GRB1;Protein brahma homolog 1;Protein BRG-1; Protein BRG1;RTPS2;SMARC A4;SMARCA4;SMCA4_HUMAN;SNF2;SNF2 beta;SNF2 like 4;SNF2-beta;SNF2B;SNF2L4;SNF2LB;Sucrose nonfermenting like 4;SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 4;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4;SWI2;Transcription activator BRG1.
Background: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4(SMARCA4) Homo sapiens The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012],
Applications: WB; IF/ICC; IP
Species Cross-Reactivity: Human; Mouse
Molecular Weight: 220
GeneID (Human): 6597
Protein MW (KDa): 220
SWISS: P51532
Source: Mouse
Research Use Only