BRI3BP Polyclonal Antibody - E-AB-53455

BRI3BP Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53455-60, E-AB-53455-120, E-AB-53455-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: BRI3BP

Target Synonym: BNAS1; BRI3 binding protein; BRI3-binding protein; BRI3B; Bri3bp; Cervical cancer 1 proto oncogene binding protein KG19; Cervical cancer 1 proto-oncogene-binding protein KG19; cervical cancer oncogene binding protein; HCCR-2; HCCR1; HCCRBP-1; I3 binding protein; I3-binding protein; KG19

Research Areas: Cancer, Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q8WY22

Background: BRI3BP (BRI3 binding protein), also known as BNAS1, HCCR-1, I3-binding protein or cervical cancer 1 proto-oncogene-binding protein KG19, is a 251 amino acid multi-pass membrane protein. Though widely expressed, BRI3BP is found at highest levels in brain, kidney and liver where it localizes to the endoplasmic reticulum (ER) and is involved in ER structural dynamics and mitochondrial viability. Possessing pro-apoptotic properties and the ability to potentiate drug-induced apoptosis, BRI3BP overexpression has been shown to enhance caspase-3 and mitochondrial cytochrome c release in etoposide-treated human embryonic kidney 293T cells.

Concentration: 0.9 mg/mL

Immunogen: Synthetic peptide of human BRI3BP

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Calculated MW: 28 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only