BRMS-1 Polyclonal Antibody - BT-AP00979

BRMS-1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00979-20, BT-AP00979-50, BT-AP00979-100

Citations, Manuals and MSDS Available upon request.

Background: BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. Breast cancer metastasis-suppressor 1 encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: BRMS1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: BRMS-1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 28461

UniProt Accession: Human: Q9HCU9; Mouse: Q99N20; Rat: Q5M7T3

Synonyms: BRMS1; Breast cancer metastasis-suppressor 1

GeneID: Human: 25855; Mouse: 107392; Rat: 100911841

Research Use Only