BTK Polyclonal Antibody-BS74994

BTK Polyclonal Antibody

Catalogue Numbers:BS74994-50, BS74994-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q06187

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB,1:500 - 1:2000 | IHC,1:50 - 1:200

Background: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Bioworld Molecular Weight: 76kDa

Specificity: Unmodification

Note: For research use only, not for use in diagnostic procedure.
Alternative Name: AGMX1;AT;ATK;BPK;IMD1;PSCTK1;XLA;BTK

Immunogen: Recombinant fusion protein of human BTK(NP_000052.1).

Conjugate: Unconjugated

Modification: Unmodified