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BUB1B Rabbit pAb - A1775

BUB1B Rabbit pAb - A1775

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BUB1B Rabbit pAb

Sizes: 20µl, 100µl

Catalogue Numbers: A1775-20, A1775-100

Citations, Manuals and SDS Available upon request.

Background: This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

Synonyms: MVA1; SSK1; BUBR1; Bub1A; MAD3L; hBUBR1; BUB1beta; BUB1B

GeneID: 701

Swiss-Prot: O60566

Reactivity: Human, Mouse, Rat

Tested Applications: ELISA, WB, IF/ICC

Calculated Molecular Weight: 120kDa

Observed Molecular Weight: 55kDa/120kDa

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human BUB1B (NP_001202.4).

Immunogen Species: Human

Host: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Research Areas: Epigenetics Nuclear Signaling, Cancer, Signal Transduction, Kinase, Cell Biology Developmental Biology, Apoptosis, Cell Cycle

Recommended Dilutions: WB: 1:500 - 1:2000 | IF/ICC: 1:50 - 1:200

Modifications: Unmodified

Conjugate: Unconjugated

Cellular Location: Chromosome, Cytoplasm, Nucleus, centromere, Centrosome, Cytoskeleton, Kinetochore, Microtubule Organizing Center

Positive Samples: U-251MG, HeLa, Jurkat, HT-29, A-549, COS-7, MCF7, DU145

Keywords: 701, sc-16195, sc-16193, sc-130708, Bub1A, BUB1B, BUB1beta, BubR1, hBUBR1, MAD3L, Protein SSK1, SSK1, BUBR1, MVA1, BUB1 mitotic checkpoint serine/threonine kinase B, mitotic checkpoint serine/threonine-protein kinase BUB1 beta, mitotic checkpoint serine/threonine kinase, MAD3/BUB1-related protein kinase, budding uninhibited by benzimidazoles 1 homolog beta, mitotic checkpoint kinase MAD3L, O60566, BUB1 Mitotic Checkpoint Serine/Threonine Kinase B, MAD3/BUB1-Related Protein Kinase, Mitotic Checkpoint Kinase MAD3L, HBUBR1, Budding Uninhibited By Benzimidazoles 1 (Yeast Homolog), Beta, Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 Beta, Budding Uninhibited By Benzimidazoles 1 Homolog Beta (Yeast), Budding Uninhibited By Benzimidazoles 1 Homolog Beta, Mitotic Checkpoint Serine/Threonine Kinase, EC 2.7.11.1, sc16195, sc 16195, sc16193, sc 16193, sc130708, sc 130708

Symbol: BUB1B

Category: Polyclonal Antibodies

Research Use Only