BUB1B Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1775-20, A1775-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 120kDa
Observed Molecular Weight: 55kDa/120kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 701
SWISS: O60566
Alternate Names: MVA1; SSK1; BUBR1; Bub1A; MAD3L; hBUBR1; BUB1beta; BUB1B
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Cancer, Signal Transduction, Kinase, Cell Biology Developmental Biology, Apoptosis, Cell Cycle.
NCBI Alias: BUB1B
Research Use Only