
BUB1B Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A1775-20, A1775-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
Synonyms: MVA1; SSK1; BUBR1; Bub1A; MAD3L; hBUBR1; BUB1beta; BUB1B
GeneID: 701
Swiss-Prot: O60566
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB, IF/ICC
Calculated Molecular Weight: 120kDa
Observed Molecular Weight: 55kDa/120kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human BUB1B (NP_001202.4).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling, Cancer, Signal Transduction, Kinase, Cell Biology Developmental Biology, Apoptosis, Cell Cycle
Recommended Dilutions: WB: 1:500 - 1:2000 | IF/ICC: 1:50 - 1:200
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Chromosome, Cytoplasm, Nucleus, centromere, Centrosome, Cytoskeleton, Kinetochore, Microtubule Organizing Center
Positive Samples: U-251MG, HeLa, Jurkat, HT-29, A-549, COS-7, MCF7, DU145
Keywords: 701, sc-16195, sc-16193, sc-130708, Bub1A, BUB1B, BUB1beta, BubR1, hBUBR1, MAD3L, Protein SSK1, SSK1, BUBR1, MVA1, BUB1 mitotic checkpoint serine/threonine kinase B, mitotic checkpoint serine/threonine-protein kinase BUB1 beta, mitotic checkpoint serine/threonine kinase, MAD3/BUB1-related protein kinase, budding uninhibited by benzimidazoles 1 homolog beta, mitotic checkpoint kinase MAD3L, O60566, BUB1 Mitotic Checkpoint Serine/Threonine Kinase B, MAD3/BUB1-Related Protein Kinase, Mitotic Checkpoint Kinase MAD3L, HBUBR1, Budding Uninhibited By Benzimidazoles 1 (Yeast Homolog), Beta, Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 Beta, Budding Uninhibited By Benzimidazoles 1 Homolog Beta (Yeast), Budding Uninhibited By Benzimidazoles 1 Homolog Beta, Mitotic Checkpoint Serine/Threonine Kinase, EC 2.7.11.1, sc16195, sc 16195, sc16193, sc 16193, sc130708, sc 130708
Symbol: BUB1B
Category: Polyclonal Antibodies
Research Use Only