C/EBP α (phospho Thr226) rabbit pAb - ES4487

C/EBP α (phospho Thr226) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4487-50, ES4487-100

Citations, Manuals and MSDS Available upon request.

Background: This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013],

Alternate Name: CEBPA; CCAAT/enhancer-binding protein alpha; C/EBP alpha

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat; Monkey

Immunogen: The antiserum was produced against synthesized peptide derived from human C/EBP-alpha around the phosphorylation site of Thr226. AA range:192-241

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 42, also have 30kd isform

Human Gene ID: 1050

Human SWISS Prot NO: P49715

Subcellular Location: Nucleus.; [Isoform 4]: Nucleus, nucleolus.

Research Use Only