Product Description

c-Kit Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16473-50, BZ16473-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P10721

Host: Rabbit

Reactivity: Human, Mouse, Rat, Monkey

Applications: WB, IHC-F, IHC-P, ICC/IF, ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background: KIT encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 110 kDa; Observed MW: 120 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry analysis of paraffin-embedded Human Mammary cancer using c-Kit antibody. High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval., Immunohistochemical analysis of paraffin-embedded Human tonsils using c-Kit antibody. High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval., Immunohistochemistry analysis of paraffin-embedded Human Mammary cancer using c-Kit antibody. High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval., Western blot analysis of c-Kit in COS7/A549 lysates using c-Kit antibody. The Lane on the right is blocked with the synthesized peptide.

Alternative Name: KIT; SCFR; Mast/stem cell growth factor receptor Kit; SCFR; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD antigen CD117

Immunogen: The antiserum was produced against synthesized peptide derived from human c-Kit. AA range:688-737

Conjugate: Unconjugated

Modification: Unmodified