Product Description

C1 Inactivator Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-60419-60, E-AB-60419-120, E-AB-60419-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: C1 Inactivator

Target Synonym: SERPING1; C1IN; C1INH; C1NH; HAE1; HAE2

Research Areas: Cardiovascular, Immunology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P05155

Background: This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human C1 Inactivator (NP_001027466.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:1000-1:2000 IF 1:50-1:200

Calculated MW: 49kDa/55kDa

Observed MW: 60kDa.110kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only