Product Description

C15orf23 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-40192-60, E-AB-40192-120, E-AB-40192-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: C15orf23

Target Synonym: KNSTRN; C15orf23; chromosome 15 open reading frame 23; HSD11; Kinastrin; Kinetochore-localized astrin-binding protein; Kinetochore-localized astrin/SPAG5-binding protein; Putative TRAF4-associated factor 1; SKAP; small kinetochore associated protein; T4AF1; TRAF4 associated factor 1; TRAF4-associated factor 1; Traf4af1

Research Areas: Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9Y448

Background: Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase . Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division.

Concentration: 2 mg/mL

Immunogen: Recombinant Human Small kinetochore-associated protein protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 35 kDa

Observed MW: 35 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only