Product Description

C1RL Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA22555-50, RA22555-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: caution:Does not associate with the C1 complex. According to PubMed:15385675 doesn't cleave the proform of complement C1s., function:Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum., induction:Up-regulated in monocytes and dendritic cells (DC) undergoing maturation or activation., similarity:Belongs to the peptidase S1 family., similarity:Contains 1 CUB domain., similarity:Contains 1 peptidase S1 domain., tissue specificity:Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV-3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast adenocarcinoma), U251 (glioma) or A549 (lung carcinoma) cells. Widely expressed in myeloid leukemia cell lines, including K-562 (chronic myelogenous leukemia), THP-1 (myelomonocytic leukemia), HL-60 and NB4 (promyelocytic leukemia), and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level).,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: Complement C1r subcomponent-like protein (C1r-LP) (C1r-like protein) (EC 3.4.21.-) (C1r-like serine protease analog protein) (CLSPa)

Clonality: Polyclonal

Dilution: WB 1:500-2000, ELISA 1:10000-20000

Molecular Weight: 53

Protein Molecular Weight (kDa): 53

Storage: -20°C/1 year

Human Gene ID: 51279

Human SwissProt Number: Q9NZP8

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only