C8 β rabbit pAb - ES8518

C8 β rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8518-50, ES8518-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],

Alternate Name: Complement component C8 beta chain (Complement component 8 subunit beta)

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000, ELISA 1:10000-20000

Reactivity: Human; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human C8B. AA range:371-420

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 70kD

Human Gene ID: 732

Human SWISS Prot NO: P07358

Subcellular Location: Secreted

Research Use Only