CA IX Monoclonal Antibody (12F10) - RA10686

CA IX Monoclonal Antibody (12F10)

Size: 50μL, 100μL

Catalogue Numbers: RA10686-50, RA10686-100

Citations, Manuals and MSDS Available upon request.

Background: carbonic anhydrase 9 (CA9) Homo sapiens Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq, Jun 2014],

Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage Instructions: -20°C/1 year

Applications: IF/ICC; WB; IHC-p; IP

Species Cross-Reactivity: Human

GeneID (Human): 768

Protein MW (KDa): 35-38

SWISS: Q16790

Source: Mouse

Research Use Only