Cables1 Polyclonal Antibody - BT-AP01073

Cables1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01073-20, BT-AP01073-50, BT-AP01073-100

Citations, Manuals and MSDS Available upon request.

Background: CABLES1 encodes a protein (Cdk5 and Abl enzyme substrate 1) involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127). Multiple transcript variants encoding different isoforms have been found for CABLES1.

Research Areas: Cell Biology

Target Protein: CABLES1

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Cables1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 67599

UniProt Accession: Human: Q8TDN4; Mouse: Q9ESJ1

Synonyms: CABLES1; CABLES; CDK5 and ABL1 enzyme substrate 1; Interactor with CDK3 1; Ik3-1

GeneID: Human: 91768; Mouse: 63955

Research Use Only