Product Description

CACNA1C Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60266-50, BS60266-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Voltage-dependent Ca++ channels mediate Ca++ entryinto excitable cellsin response to membrane depolarization, and they are involved in a variety of Ca++-dependent processes, includingmuscle contraction, hormone or neurotransmitter release and gene expression. Calciumchannels are highly diverse, mμltimericcomplexescomposed of anα-1 subunit, an intracellμlar β-subunit, a disμlfide linkedα-2/δ subunit and a transmembrane γ-subunit. Ca++ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types.L-type Ca++ currentsinitiate muscle contraction, endocrine secretion, and gene transcription, and can be regμlated through second-messenger activated protein phosphorylation pathways.L-type calcium channels may form macromolecμlar signaling complexeswith G protein-coupled receptors, thereby enhancing the selectivity of regμlating specifictargets.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Voltage-dependent L-type calcium channel subunit alpha-1C, Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle, Voltage-gated calcium channel subunit alpha Cav1.2, CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human CACNA1C.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CACNA1C polyclonal antibody detects endogenous levels of CACNA1C protein.

Molecular Weight: ~ 249 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q13936

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only