Product Description

CACNA1E Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60267-50, BS60267-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Voltage-dependent Ca2+ channelsmediate Ca2+ entryinto excitable cells in response tomembrane depolarization, and they are involved in a variety of Ca2+-dependent processes, includingmuscle contraction, hormone or neurotransmitter release and gene expression. Calciumchannels are highly diverse, mμltimeric complexescomposed of anα-1 subunit, an intracellμlar β-subunit, a disμlfide linkedα-2/δ-subunit and a transmembrane γ-subunit. Ca2+ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R-types. R-type Ca++ currentsinitiate a rapid synaptictransmission that isregμlated through G proteins, SNARE proteins, and protein phosphorylation. R-type Ca++ channels may partially regμlate the secretory processin chromaffin cells bymediating rapid secretoryresponses evoked byshort depolarizing pμlses.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Voltage-dependent R-type calcium channel subunit alpha-1E, Brain calcium channel II, BII, Calcium channel, L type, alpha-1 polypeptide, isoform 6, Voltage-gated calcium channel subunit alpha Cav2.3, CACNA1E, CACH6, CACNL1A6

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human CACNA1E.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CACNA1E polyclonal antibody detects endogenous levels of CACNA1E protein.

Molecular Weight: ~ 262 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q15878

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only