Cadherin-20 rabbit pAb - ES5578

Cadherin-20 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5578-50, ES5578-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008],

Alternate Name: CDH20; CDH7L3; Cadherin-20

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human CDH20. AA range:111-160

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 28316

Human SWISS Prot NO: Q9HBT6

Subcellular Location: Cell membrane; Single-pass type I membrane protein.

Research Use Only