Cadherin-23 Polyclonal Antibody - BT-AP01101

Cadherin-23 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01101-20, BT-AP01101-50, BT-AP01101-100

Citations, Manuals and MSDS Available upon request.

Background: CDH23 (cadherin related 23) is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. CDH23 is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of CDH23 may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.

Research Areas: Others

Target Protein: CDH23

Applications: IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Cadherin-23 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 369525

UniProt Accession: Human: Q9H251; Mouse: Q99PF4; Rat: P58365

Synonyms: CDH23; KIAA1774; KIAA1812; Cadherin-23; Otocadherin

GeneID: Human: 64072; Mouse: 22295; Rat: 114102

Research Use Only