Cadherin-23 rabbit pAb - ES7147

Cadherin-23 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7147-50, ES7147-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013],

Alternate Name: CDH23; KIAA1774; KIAA1812; Cadherin-23; Otocadherin

Source: Rabbit

Applications: IF; ELISA

Dilution: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human CDH23. AA range:61-110

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 64072

Human SWISS Prot NO: Q9H251

Subcellular Location: Cell membrane; Single-pass type I membrane protein.

Research Use Only