Cadherin 5 Monoclonal Antibody-MB11762

Cadherin 5 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11762-50, MB11762-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P55284

Host: Rabbit

Reactivity: Mouse

Applications: WB,ICC/IF,IP

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of VE Cadherin in mouse lungLysates using Cadherin 5 antibody.

Bioworld Molecular Weight: Calculated MW: 88 kDa; Observed MW: 90-140 kDa

Specificity: IgG

Alternative Name: 7B4; Vec; VECD; Cd144; VEcad; VE-Cad; AA408225

Immunogen: Recombinant protein of mouse VE Cadherin

Conjugate: Unconjugated

Modification: Unmodified