Cadherin Monoclonal Antibody-MB11371

Cadherin Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11371-50, MB11371-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P12830/P22223/P19022

Host: Rabbit

Reactivity: Human, Mouse, Rat, Hamster

Applications: WB, IHC-F, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 97 kDa; Observed MW: 130-150 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of pan Cadherin in mouse heart, mouse brain lysates using Cadherin antibody., Western blot analysis of pan Cadherin in Hela, CHO-K1, C6, rat Brain lysates using pan Cadherin antibody., Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using pan Cadherin antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunocytochemistry analysis of pan Cadherin in MCF-7 using pan Cadherin antibody, and DAPI.

Alternative Name: CDHP; CDHE; HJMD; PCAD; CDHN; P-cadherin; E-cadherin; N-cadherin; Cadherin-1; Cadherin-2; Cadherin-3

Immunogen: A synthetic peptide of human pan Cadherin

Conjugate: Unconjugated

Modification: Unmodified