Calbindin Polyclonal Antibody-BS90168

Calbindin Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS90168-50, BS90168-100 Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Swiss-Prot: P05937(Human) P12658(Mouse) P07171(Rat) Host: Rabbit Reactivity: Human, Mouse, Rat Applications: WB, ICC/IF, IHC All Applications: WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 Background: The family of EF-hand type Ca²⁺-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 α and β, Calgranulin A (also designated MRP8), Calgranulin B (also designated MRP14), Calgranulin C and the Parvalbumin family members, including Parvalbumin α and Parvalbumin β (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261 amino acid protein with six EF-hand domains, four of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function. Purification and Purity: ProA affinity purified Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Specificity: Calbindin polyclonal antibody detects endogenous levels of Calbindin protein. Bioworld Molecular Weight: 28 kDa Note: For research use only, not for use in diagnostic procedure. Extra Notes: Western blot analysis of Calbindin on different lysates using anti-Calbindin antibody at 1/1,000 dilution. Positive control: Lane 1: Rat brain Lane 2: Mouse kidney, ICC staining Calbindin in PC-12 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. Alternative Name: CALB1, avian-type, CAB27, CALB 1, CALB, CALB1, CALB1, Calbindin 1 28kDa, Calbindin, Calbindin D28, D 28K, D-28K, D28K, OTTHUMP00000166027, OTTHUMP00000225441, Rt VL H protein, Vitamin D dependent calcium binding protein, Vitamin D dependent calcium binding protein avian type, Vitamin D-dependent calcium-binding protein, Immunogen: recombinant protein Conjugate: Unconjugated Modification: Unmodified