Product Description

Calcineurin A Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS90169-50, BS90169-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regμlating a broad range of cellμlar functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regμlatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2B family comprises subfamily members PP2B-Aα, PP2B-Aβ and PP2B-Aγ. Two additional regμlatory subunits been identified, designated PP2B-B1 and PP2B-B2.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IF

Alternate Names: PPP3CA, Alpha isoform formerly PPP2B, Calcineurin A alpha, Calcineurin A1, CalcineurinA, Calmodμlin dependent calcineurin A subunit alpha isoform, Calmodμlin-dependent calcineurin A subunit alpha isoform, CALN, CALNA 1, CALNA, CALNA1, CAM PRP catalytic subunit, CAM-PRP catalytic subunit, CCN 1, CCN1, CNA 1, CNA alpha, CNA, CNA1, PP2BA, PPP2B, Ppp3ca, Protein phosphatase 2B catalytic subunit, Protein phosphatase 3 (formerly 2B) catalytic subunit alpha isoform, Protein phosphatase 3 catalytic subunit alpha isoform PPP3CA, Protein phosphatase 3 catalytic subunit alpha isozyme, Serine/threonine protein phosphatase 2B catalytic subunit alpha isoform

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein.

Dilution: WB:1:2000~1:5000
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Calcineurin A polyclonal antibody detects endogenous levels of Calcineurin A protein.

Molecular Weight: ~ 59 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q08209

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only