Calcineurin A Polyclonal Antibody-BS90169

Calcineurin A Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS90169-50, BS90169-100

Swiss-Prot: Q08209

Host: Rabbit

Calcineurin A Polyclonal Antibody-BS90169

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human

Applications: WB, IF

All Applications: WB:1:2000~1:5000
IF: 1:50~1:200

Background: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2B family comprises subfamily members PP2B-Aα, PP2B-Aβ and PP2B-Aγ. Two additional regulatory subunits been identified, designated PP2B-B1 and PP2B-B2.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Calcineurin A polyclonal antibody detects endogenous levels of Calcineurin A protein.

Bioworld Molecular Weight: ~ 59 kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Calcineurin A pAb at 1:2000 dilution
Lane 1: EC9706 whole cell lysate (40ug)
Lane 2: U-87MG whole cell lysate (40ug), Immunofluorescence analysis of U-87MG cells using Calcineurin A antibody at dilution of 1:50.

Alternative Name: PPP3CA, Alpha isoform formerly PPP2B, Calcineurin A alpha, Calcineurin A1, CalcineurinA, Calmodulin dependent calcineurin A subunit alpha isoform, Calmodulin-dependent calcineurin A subunit alpha isoform, CALN, CALNA 1, CALNA; CALNA1; CAM PRP catalytic subunit; CAM-PRP catalytic subunit; CCN 1; CCN1; CNA 1; CNA alpha; CNA; CNA1; PP2BA; PPP2B; Ppp3ca, Protein phosphatase 2B catalytic subunit; Protein phosphatase 3 (formerly 2B) catalytic subunit alpha isoform; Protein phosphatase 3 catalytic subunit alpha isoform PPP3CA; Protein phosphatase 3 catalytic subunit alpha isozyme; Serine/threonine protein phosphatase 2B catalytic subunit alpha isoform

Immunogen: Recombinant protein.

Modification: Unmodified

Conjugate: Unconjugated