Product Description

Calcipressin 3 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65689-50, BS65689-100

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Swiss-Prot: Q9UKA8

Host: Rabbit

Reactivity: Human, Mouse, Rat,Chicken,Dog, Pig, Cow, Rabbit, Sheep,

Applications: WB

All Applications: WB=1:500-2000

Background: Calcineurin is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions. Proteins belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFATs (Nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. Calcipressin-2, also known as RCAN2 and DSCR1L1 (Down syndrome candidate region 1-like 1), is a 197 amino acid protein that is highly expressed in both the cytoplasm and nucleus of neurons and is the only RCAN family member that is found in glial cells. Calcipressin-3, also known as RCAN3 and DSCR1L2 (Down syndrome candidate region 1-like protein 2), is a 241 amino acid protein that potentially is involved in central nervous system development. Calcipressin-3 interacts with cardiac troponin I, suggesting that it may play a role in cardiac contraction events.

Purification and Purity: affinity purified by Protein A

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Calcipressin 3 Polyclonal Antibody detects endogenous levels of Calcipressin 3 protein.

Bioworld Molecular Weight: 27 kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti- Calcipressin 3 at 1/1000 dilution

Alternative Name: Calcipressin-3; Down syndrome candidate region 1 like 2; regulator of calcineurin 3; Down syndrome candidate region 1 like protein 2; Down syndrome candidate region 1-like protein 2; Down syndrome critical region gene 1 like 2; DSCR1L2; hRCN3; MCIP3; Myocyte enriched calcineurin interacting protein 3; Myocyte-enriched calcineurin-interacting protein 3; RCAN family member 3; RCAN3; RCAN3_HUMAN; RCN3; RCN3; MCIP3; Regulator of calcineurin 3.

Immunogen: KLH conjugated synthetic peptide derived from human Calcipressin 3

Conjugate: Unconjugated

Modification: Unmodified