CALD1 Polyclonal Antibody - E-AB-60930

CALD1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-60930-60, E-AB-60930-120, E-AB-60930-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CALD1

Target Synonym: CALD1; CDM; H-CAD; HCAD; L-CAD; LCAD; NAG22; caldesmon

Research Areas: Cancer,Cardiovascular,Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q05682

Background: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human CALD1

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 61kDa/62kDa/64kDa/65kDa/93kDa

Observed MW: 85kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only