Product Description

Caldesmon (Ab-759) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65240-50, BS65240-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: caldesmon 1(CALD1) Homo sapiens This gene encodes a calmodμlin- and actin-binding protein that plays an essential role in the regμlation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodμlin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene resμlts in mμltiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jμl 2008],

Category: Primary Antibody

Reactivity: Human

Host: Mouse/IgG2b, Kappa

Applications: IHC-p, IF(paraffin, section)

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthesized peptide derived from human Caldesmon

Dilution: IHC-p 1:100-500，WB 1:500-2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity: This antibody detects endogenous levels of human Caldesmon. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section

Molecular Weight: /

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q05682

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only