Caldesmon Monoclonal Antibody-MB11945

Caldesmon Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11945-50, MB11945-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q05682

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 93 kDa; Observed MW: 80 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Caldesmon/CDM in Hela, C6 lysates using Caldesmon antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Caldesmon/CDM antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22

Immunogen: A synthetic peptide of human Caldesmon/CDM

Conjugate: Unconjugated

Modification: Unmodified