Caldesmon Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-13956-60, E-AB-13956-120, E-AB-13956-200 Citations, Manuals and MSDS Available upon request. Abbreviation: CALD1 Target Synonym: CAD; CALD 1; CALD1; CALD1; Caldesmon 1; Caldesmon 1 Isoform 1; Caldesmon 1 Isoform 2; Caldesmon 1 Isoform 3; Caldesmon 1 Isoform 4; Caldesmon 1 Isoform 5; Caldesmon; Caldesmon1; CDM; H CAD; HCAD; L CAD; LCAD; MGC21352; NAG22 Research Areas: Cancer, Cardiovascular, Signal Transduction Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human, Rat Application: WB, IHC, ELISA Isotype: IgG Clonality: Polyclonal UNIProt ID: Q05682 Background: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.  Concentration: 0.4 mg/mL Immunogen: Recombinant protein of human Caldesmo Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4 Purification Method: Affinity purification Dilution: WB 1:1000-1:5000, IHC 1:50-1:150 Calculated MW: 63kDa Storage: -20°C/One year. Avoid freeze / thaw cycles. Shipping: Ice bag Research Use Only