CALHM1 rabbit pAb - ES20805

CALHM1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20805-50, ES20805-100

Citations, Manuals and MSDS Available upon request.

Background: calcium homeostasis modulator 1 (CALHM1) Homo sapiens This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations, but the pathogenicity of this polymorphism is unclear.[provided by RefSeq, Mar 2010],

Alternate Name: Calcium homeostasis modulator protein 1; Protein FAM26C

Source: Rabbit

Applications: WB; IHC; IF

Dilution: WB: 1:500-1000 IHC: 1:200-500

Reactivity: Human; Rat

Immunogen: Synthetic Peptide of CALHM1 AA range: 204-254

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Observed Band (KD): 40kD

Human Gene ID: 255022

Human SWISS Prot NO: Q8IU99

Subcellular Location: Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Colocalizes with HSPA5 at the endoplasmic reticulum (PubMed:18585350). Localizes to the basolateral membrane of epithelial cells including taste cells (By similarity).

Research Use Only