Calpain 2 (Phospho Ser50) rabbit pAb - ES20175

Calpain 2 (Phospho Ser50) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20175-50, ES20175-100

Citations, Manuals and MSDS Available upon request.

Background: The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],

Alternate Name: Calpain-2 catalytic subunit (EC 3.4.22.53; Calcium-activated neutral proteinase 2; CANP 2; Calpain M-type; Calpain large polypeptide L2; Calpain-2 large subunit; Millimolar-calpain; M-calpain)

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human Calpain 2 (Phospho Ser50)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 69kD

Human Gene ID: 824

Human SWISS Prot NO: P17655

Subcellular Location: Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca (2+) binding.

Research Use Only