Product Description

Calregulin (G54) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2264-50, BS2264-100

Sizes: 50µl, 100µl

Swiss-Prot: P27797

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Calregulin (G54) polyclonal antibody detects endogenous levels of Calregulin protein

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Calregulin (G54) pAb at 1:500 dilution
Lane 1: L02 whole cell lysate (40ug)
Lane 2: MCF-7 whole cell lysate (40ug)
Lane 3: The Brain tissue lysate of Mouse (40ug)
Lane 4: The Brain tissue lysate of Rat (40ug), Immunohistochemistry (IHC) analyzes of Calregulin (G54) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 60 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Calreticulin; CRP55; Calregulin; Endoplasmic reticulum resident protein 60; ERp60; HACBP; grp60; CALR; CRTC

Immunogen: Synthetic peptide, corresponding to amino acids 20-70 of Human Calregulin.

Conjugate: Unconjugated

Modification: Unmodified