Product Description

Calsequestrin 1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90175-50, BS90175-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P31415(Human) O09165(Mouse) P19633(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC FC

All Applications: WB:1:500
IHC:1:50-1:200
FC:1:50-1:100

Background: Calsequestrin (CS, also known as CSQ) is the major calcium-binding protein of cardiac and skeletal muscle whose function is to sequester calcium in the lumen of the sarcoplasmic reticulum (SR). In mammals, there are two forms of this protein, calsequestrin 1 and calsequestrin 2, which encode fast-twitch skeletal muscle and cardiac calsequestrin, respectively. Calsequestrin 1, also known as Calmitin, is located in the terminal cisternae luminal spaces of the SR of fast skeletal muscle cells. Calsequestrin 2 is present in terminal cisternae luminal spaces of the SR of both cardiac and slow skeletal muscle cells. In addition, calsequestrin regulates the ryanodine receptor signaling (RyR) through Triadin and Junctin.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Calsequestrin 1 polyclonal antibody detects endogenous levels of Calsequestrin 1 protein.

Bioworld Molecular Weight: 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemical analysis of paraffin-embedded rat skeletal muscle tissue using anti-Calsequestrin 1 antibody. Counter stained with hematoxylin., Immunohistochemical analysis of paraffin-embedded human fetal skeletal muscle tissue using anti-Calsequestrin 1 antibody. Counter stained with hematoxylin.

Alternative Name: CASQ1, CASQ, Calmitin, Calmitine, Calsequestrin 1 (fast twitch, skeletal muscle), Calsequestrin, Calsequestrin, cell, Calsequestrin, skeletal muscle isoform, Calsequestrin-1, CASQ, Casq1, CASQ1, PDIB1, skeletal muscle isoform,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified