Product Description

CALU Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66536-50, MB66536-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Calumenin belongs to the CREC family of proteins that also contains reticμlocalbin, ERC-55/TCBP-49/E6BP, Cab45, and crocalbin/CBP-50. These EF-hand proteins localize to the endoplasmic reticμlum (ER) and are involved in the secretory pathway in mammalian cells. Calumenin exists as two isoforms corresponding to alternativly spliced variants of the CALU gene. Calumenin has been shown to localize to the ER via a carboxy terminal HDEF ER retention signal, and undergoes secretion after trafficking through the secretory pathway. Secreted calumenin plays a role in amyloidosis by interacting with serum amyloid P component. Calumenin is also a chaperone for mutants of the cystic fibrosis transmembrane conductance regμlator (CFTR). Researchers performing a proteomics analysis of endometrial cancer identified calumenin as a potential target for endometrial carcinoma.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Mouse

Applications: WB

Alternate Names: Calumenin, Crocalbin, IEF SSP 9302

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Purified recombinant human Calumenin protein fragments expressed in E.coli.

Dilution: WB (1/500 - 1/1000)

Purification: The antibody was purified by immunogen affinity chromatography.

Specificity: Recognizes endogenous levels of CALU protein.

Molecular Weight: ~ 47 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O43852

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only