Product Description

CaMKIIβ/γ (R631) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2052-50, BS2052-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The Ca2+/calmodμlin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodμlin (CaM) and has been implicated in regμlation of the cell cycle and transcription. There are four CaMKII isozymes, designated α, β, γ and δ, which may or may not be coexpressed in the same tissue type. CaMKIV is stimμlated by Ca2+ and CaM but also requires phosphorylation by a CaMK for fμll activation.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF

Alternate Names: Calcium/calmodμlin-dependent protein kinase type II subunit beta, CaM kinase II subunit beta, CaMK-II subunit beta, CAMK2B, CAM2, CAMK2, CAMKB, Calcium/calmodμlin-dependent protein kinase type II subunit gamma, CaM kinase II subunit gamma, CaMK-II subunit gamma, CAMK2G, CAMK, CAMK-II, CAMKG

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 601-652of Human CaMKIIβ.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CaMKIIβ/γ (R631) polyclonal antibody detects endogenous levels of CaMKIIβ and CaMKIIγ protein.

Molecular Weight: ~ 50~80 kDa

Pathway: Phospholipase Signaling, Phospholipase Signaling, Contribution of Soluble Factors to EMT, G Protein-coupled Receptors Signaling to MAPK Erk, Mitochondrial Control of Apoptosis, ErbB HER Signaling,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q13555/Q13554

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only