CaMKK2 (phospho-Ser511) Rabbit Polyclonal Antibody - RA22685

CaMKK2 (phospho-Ser511) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA22685-50, RA22685-100

Citations, Manuals and MSDS Available upon request.

Background: calcium/calmodulin dependent protein kinase kinase 2 (CAMKK2) Homo sapiens The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca (2+) /calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK) . This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000

Alternative Names: Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 10645

Protein MW (KDa): 65

SWISS: Q96RR4

Source: Rabbit

Research Use Only