CaMKV Polyclonal Antibody - BT-AP01151

CaMKV Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01151-20, BT-AP01151-50, BT-AP01151-100

Citations, Manuals and MSDS Available upon request.

Background: The Ca2+/calmodulin-dependent protein kinases (CaMKs) comprise a structurally related subfamily of serine/threonine kinases. CAMKV (CaM kinase-like vesicle-associated), also known as 1G5 or VACAMKL, is a 501 amino acid protein that localizes to cytoplasmic vesicles, as well as to the cell membrane, and contains one protein kinase domain. Although a member of the CaMK family, CaMKV is thought to be catalytically inactive, but it may play a role in vesicle function and nervous system development. Multiple isoforms of CaMKV exist due to alternative splicing events. The gene encoding CaMKV maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Research Areas: Signal Transduction

Target Protein: CAMKV

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: CaMKV Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 54354

UniProt Accession: Human: Q8NCB2; Mouse: Q3UHL1; Rat: Q63092

Synonyms: CAMKV; CaM kinase-like vesicle-associated protein

GeneID: Human: 79012; Mouse: 235604; Rat: 79011

Research Use Only