CAPN7 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A17666-20, A17666-100
Citations, Manuals and MSDS Available upon request.
Background: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 93kDa
Observed Molecular Weight: 93kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 23473
SWISS: Q9Y6W3
Alternate Names: PALBH; CALPAIN7; CAPN7
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Ubiquitin, Neuroscience, Calcium Signaling.
NCBI Alias: CAPN7
Research Use Only