Product Description

CARD4 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65975-50, BS65975-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellμlar bacterial lipopolysaccharides (LPS). Forms an intracellμlar sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens. Required for RHOA and RIPK2 dependent NF-kappa-B signaling pathways activation upon S.flexneri cell invasion. Involved not only in sensing peptidoglycan (PGN)-derived muropeptides but also in the activation of NF-kappa-B by Shigella effector proteins IpgB2 and OspB.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: CARD 4, CARD4, Caspase recruitment domain 4, Caspase recruitment domain containing protein 4, Caspase recruitment domain family member 4, Caspase recruitment domain protein 4, Caspase recruitment domain-containing protein 4, CLR 7.1, CLR7.1, NLR family CARD domain containing 1, NLRC 1, NLRC1, NOD 1, Nod1, NOD1 protein, NOD1_HUMAN, Nucleotide binding oligomerization domain containing 1, Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 1, Nucleotide-binding oligomerization domain-containing protein 1, Protein Nod1.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human CARD4:51-150/953

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: CARD4 Polyclonal Antibody detects endogenous levels of CARD4 protein.

Molecular Weight: 108 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9Y239

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only