Cardiotrophin-1 (H31) Polyclonal Antibody-BS3672

Cardiotrophin-1 (H31) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS3672-50, BS3672-100

Sizes: 50µl, 100µl

Swiss-Prot: Q16619

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: Cardiotrophin-1 (CT-1) is a member of the IL-6 family of cytokines, which signal through gp130 receptor complexes. gp130 complexes with several different receptor subunits to transmit signals from Cardiotrophin-1, IL-6, LIF, OSM, CNTF and IL-11. Cardiotrophin-1 binds to and activates the leukemia inhibitory factor (LIF) receptor/gp130 receptor complex and has been shown to induce hypertrophy in cardiac myocytes in vitro. Cardiotrophin-1, a secreted protein expressed at high levels in myocardium during cardiogenesis, has been shown to promote proliferation and survival of embryonic cardiomyocytes, suggesting a role for Cardiotrophin-1 in the activation of gp130 during cardiac development.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Cardiotrophin-1 (H31) polyclonal antibody detects endogenous levels of Cardiotrophin-1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Cardiotrophin-1 (H31) pAb at 1:500 dilution
Lane 1: PC3 whole cell lysate (40ug)
Lane 2: K562 whole cell lysate (20ug)
Lane 3: Jurkat whole cell lysate (40ug)
Lane 4: The Muscle tissue lysate of Mouse (40ug)
Lane 5: H9C2 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of Cardiotrophin-1 (H31) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~ 21 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Cardiotrophin-1; CT-1; CTF1; Cardiotrophin1; CT1; Cardiotrophin 1; CT 1;

Immunogen: Synthetic peptide, corresponding to amino acids 1-53 of Human CT-1.

Conjugate: Unconjugated

Modification: Unmodified