CARKL Polyclonal Antibody - BT-AP01173

CARKL Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01173-20, BT-AP01173-50, BT-AP01173-100

Citations, Manuals and MSDS Available upon request.

Background: The sedoheptulokinase encoded by SHPK has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.

Research Areas: Signal Transduction; Metabolism

Target Protein: SHPK

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: CARKL Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 51504

UniProt Accession: Human: Q9UHJ6; Mouse: Q9D5J6

Synonyms: SHPK; CARKL; Sedoheptulokinase; SHK; Carbohydrate kinase-like protein

GeneID: Human: 23729; Mouse: 74637

Research Use Only