Casein Kinase IIAlpha Polyclonal Antibody - BT-AP01178

Casein Kinase IIAlpha Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01178-20, BT-AP01178-50, BT-AP01178-100

Citations, Manuals and MSDS Available upon request.

Background: Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein (casein kinase 2 alpha 1) encoded by CSNK2A1 represents the alpha subunit. While CSNK2A1 is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for CSNK2A1.

Research Areas: Cell Biology

Target Protein: CSNK2A1

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Casein Kinase IIalpha Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 45144

UniProt Accession: Human: P68400; Mouse: Q60737; Rat: P19139

Synonyms: CSNK2A1; CK2A1; Casein kinase II subunit alpha; CK II alpha

GeneID: Human: 1457; Mouse: 12995; Rat: 116549

Research Use Only