CASP7 Polyclonal Antibody - E-AB-30758

CASP7 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-30758-60, E-AB-30758-120, E-AB-30758-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: Caspase-7

Target Synonym: Apoptotic protease Mch-3; Apoptotic protease MCH3; CASP-7; CASP7; CASP7; Caspase 7; Caspase 7 apoptosis related cysteine peptidase; Caspase-7 subunit p11; Caspase7; CMH 1; CMH-1; CMH1; ICE LAP3; ICE-LAP3; ICE-like apoptotic protease 3; LICE2; MCH3

Research Areas: Cancer, Cell Biology, Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB, IHC-p, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P55210

Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Overexpression promotes programmed cell death.

Concentration: 1 mg/mL

Immunogen: Synthesized peptide derived from the N-terminal region of human Caspase-7.

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ICC 1:200-1:1000, ELISA 1:5000

Calculated MW: 34kDa

Observed MW: 35kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only