Product Description

Caspase 1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BZ16427-50, BZ16427-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regμlatory element binding proteins (SREBPs). Can also promote apoptosis.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC-P, ELISA

Alternate Names: CASP1, IL1BC, IL1BCE, Caspase-1, CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: The antiserum was produced against synthesized peptide derived from human Caspase 1. AA range:342-391

Dilution: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 45 kDa, Observed MW: 45 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P29466

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only