Caspase 1 Polyclonal Antibody-BZ16427

Caspase 1 Polyclonal Antibody

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16427-50, BZ16427-100

Swiss-Prot: P29466

Host: Rabbit

Caspase 1 Polyclonal Antibody-BZ16427

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Purification and Purity: Affinity Purified

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 45 kDa; Observed MW: 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Caspase 1 in variousLysates using Caspase 1 antibody., Immunohistochemistry analysis of paraffin-embedded Human stomach using Caspase 1 antibody.High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.

Alternative Name: CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45

Immunogen: The antiserum was produced against synthesized peptide derived from human Caspase 1. AA range:342-391

Modification: Unmodified

Conjugate: Unconjugated