Caspase-12 Polyclonal Antibody
Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Sizes: 50µl, 100µl
Catalogue Numbers: BS65665-50, BS65665-100
Swiss-Prot: O08736
Host: Rabbit
Caspase-12 Polyclonal Antibody-BS65665
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Reactivity: Mouse, Rat,
Applications: WB,
All Applications: WB=1:500-2000
Background: Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011].
Purification and Purity: affinity purified by Protein A
Specificity: Caspase-12 Polyclonal Antibody detects endogenous levels of Caspase-12 protein.
Bioworld Molecular Weight: 46 kD
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Sample:
Cerebrum (Mouse) Lysate at 40 ug
Cerebrum (Rat) Lysate at 40 ug
Primary: Anti-alpha smooth muscle Actin at 1/300 dilution, Sample:
Lane 1: Muscle (Mouse) Tissue Lysate at 40 ug
Lane 2: Muscle (Rat) Tissue Lysate at 40 ug
Primary: Anti-Caspase-12 at 1/1000 dilution
Alternative Name: UNQ9415; Apoptosis related cysteine protease; CASP 12; casp12; CASP12P1; Caspase 12 pseudogene 1; CASP-12; casp12; caspase 12 (gene/pseudogene); Caspase12; CASPC_HUMAN; OTTHUMP00000207026; OTTHUMP00000207028; OTTHUMP00000207031; OTTHUMP00000207032; OTTHUMP00000219058; UNQ9415.
Immunogen: KLH conjugated synthetic peptide derived from the middle of human Caspase-12
Modification: Unmodified
Conjugate: Unconjugated