Caspase-2 (phospho Ser157) Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA22731-50, RA22731-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: caspase 2 (CASP2) Homo sapiens This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011], Reactivity: Human, Rat, Mouse Host: Rabbit Applications: IHC-p, IF (paraffin section), ELISA Alternate Names: CASP2, ICH1, NEDD2, Caspase-2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1 Clonality: Polyclonal Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. Storage: -20°C/1 year Human Gene ID: 835 Human SwissProt Number: P42575 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only