Caspase 6 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB10242-50, MB10242-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P55212
Host: Rabbit
Reactivity: Human, Rat
Applications: WB
All Applications: WB: 1/500-1/1000
Background: Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Caspase6 in Jurkat, C6Lysates using Caspase 6 antibody.
Bioworld Molecular Weight: Calculated MW: 33 kDa; Observed MW: 11,33 kDa
Specificity: IgG
Alternative Name: CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
Immunogen: Recombinant protein of human Caspase-6
Conjugate: Unconjugated
Modification: Unmodified