Caspase-7 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1524-20, A1524-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 34kDa
Observed Molecular Weight: 35kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 840
SWISS: P55210
Alternate Names: MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3; Caspase-7
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Invasion and Metastasis, Signal Transduction, ErbB-HER Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Caspases, Inhibition of Apoptosis, Death Receptor Signaling Pathway, Endocrine Metabolism, Neuroscience, Neurodegenerative Diseases.
NCBI Alias: CASP7
Research Use Only