Caspase 9 (1D1) Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB3050-50, MB3050-100
Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Swiss-Prot: P55211
Host: Mouse
Reactivity: Human
Applications: WB
All Applications: WB: 1/500-1/1000
Background: Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Caspase9 in A549, MCF-7, Jurkat, K562 and HelaLysates using Caspase9 antibody.
Bioworld Molecular Weight: Calculated MW: 46 kDa; Observed MW: 49,37 kDa
Specificity: IgG1
Alternative Name: CASP9; MCH6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6
Immunogen: Purified recombinant human Caspase-9 protein fragments expressed in E.coli.
Conjugate: Unconjugated
Modification: Unmodified