Product Description

CAST (Calpastatin) Mouse Monoclonal Antibody

Sizes: 25μl, 100μl

Catalogue Numbers: MB4345-25, MB4345-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regμlatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: FC, IHC, WB

Alternate Names: BS-17, PLACK

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Fμll length human recombinant protein of human CAST(NP_001741) produced in HEK293T cell.

Dilution: WB 1:2000, IHC 1:150, FLOW 1:100

Purification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IgG1

Molecular Weight: 84.8 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P20810

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only