Catalase rabbit pAb - ES3885

Catalase rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3885-50, ES3885-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009],

Alternate Name: CAT; Catalase

Source: Rabbit

Applications: IF; WB; IHC; ELISA

Dilution: IF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse; ; Fish

Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human CAT. AA range:478-527

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 60kD

Human Gene ID: 847

Human SWISS Prot NO: P04040

Subcellular Location: Peroxisome.

Research Use Only