Product Description

Catenin-α1/2 (P940) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS1040-50, BS1040-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: a-catenins are a group of proteins associated with cadherin cell-cell adhesion molecμles and play indispensable roles in the function of the cadherins. a N-catenin is a linker between cadherin adhesion receptors and the Actin cytoskeleton and is essential for stabilizing dendritic spines in rodent hippocampal neurons in cμlture. A deletion in this protein causes cerebellar and hippocampal lamination defects and impaired startle reaction. a E- and a N-catenin appear to co-localize in cell bodies of neurons in dorsal root ganglia. In mice, a N-catenin was found to occur at the roof plate of the mesencephalon and diencephalon, coinciding with Wnt-1 expression.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF, IP

Alternate Names: Catenin alpha-1, Alpha E-catenin, Cadherin-associated protein, Renal carcinoma antigen NY-REN-13, CTNNA1, Catenin-α1, Catenin α1, αE-catenin, Catenin alpha-2, Alpha N-catenin, Alpha-catenin-related protein, CTNNA2, CAPR, Catenin-α2, Catenin α2, αN-catenin,

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Synthetic peptide, corresponding to amino acids C-terminus of Human Catenin-α2.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200
IF: 1:50~1:200
IP: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Catenin-α1/2 (P940) polyclonal antibody detects endogenous levels of Catenin-α1/2 protein.

Molecular Weight: ~ 100 kDa

Pathway: Wntβ catenin signaling，Wntβ catenin signaling，Contribution of ECM and Cytoskeletal Factors to EMT,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P35221/P26232

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only